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Ena Respiratory
11 Sep 2023

New Data From an Influenza Challenge Study Further Support the Prophylactic Potential of INNA-051 to Accelerate Viral Clearance

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— INNA-051 increased early expression of multiple antiviral effector genes compared with placebo and shortened viral shedding duration in participants with confirmed influenza infection

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29 Aug 2023

ENA Respiratory Expands Leadership Team and Extends U.S. Department of Defense Funding to Enable Phase II Program of INNA-051 in Community-Acquired Viral Respiratory Infections

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— $3.8 million DOD contract extension to fund non-clinical safety studies; three-month seasonal prophylaxis Phase 2b study in at-risk populations, – elderly with comorbidities, including chronic lung diseases and diabetes.

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14 Feb 2023

Nasal Spray Significantly Accelerates Respiratory Virus Clearance in Phase 2a Clinical Study

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— Post hoc analyses found a statistically significant reduction in the duration of flu infection and a dose-related trend toward a reduction in symptom duration.  

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30 Jan 2023

Survey demonstrates that individuals with COPD seek more options to reduce risks of seasonal respiratory viral infections

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— ENA Respiratory and COPD Foundation survey confirms patients are overwhelmingly positive about taking an immune-modulating nasal spray to reduce lung disease exacerbations.

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09 Jan 2023

ENA Respiratory Awarded $4.38 Million U.S. Department of Defense Agreement to Fund Development of Broad-Spectrum Antiviral INNA-051

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Goal is to add new medical countermeasure (MCM) against known and emerging viral respiratory threats

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13 May 2022

Safety and Tolerability of the Toll-Like Receptor (TLR)2/6 Agonist INNA-051 in Healthy Adults

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2022 ATS International Conference May 13-18, 2022, San Francisco, USA

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11 May 2022

ENA Respiratory Selected for BLUE KNIGHT™ to Accelerate Development of Pan-Antiviral Nasal Spray

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ENA Respiratory, a clinical-stage pharmaceutical company developing INNA-051, a first-in-class broad-spectrum antiviral innate immunomodulator for pan-antiviral prophylaxis in at-risk populations and pandemic preparedness, has been selected to join BLUE KNIGHT™

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15 Mar 2022

First Participants Dosed in Phase 2a Study of Pan-Antiviral Nasal Spray

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ENA Respiratory begins influenza challenge study for fast-acting nasal spray INNA-051, designed
to boost innate immunity in patients at high risk of severe complications from respiratory infections

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23 Feb 2022

ENA Respiratory and the COPD Foundation Partner to Develop Pan-Antiviral Nasal Spray

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INNA-051 is being developed to stimulate innate immunity and reduce the incidence and severity of respiratory viral infections, such as COVID-19, rhinovirus, or influenza in populations at-risk of complications that include individuals with COPD.

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28 Sep 2021

First-in-Class, Broad-Spectrum Nasal Spray to Prevent COVID-19 and Other Common Respiratory Illnesses Set to Begin Phase 2 Trials

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ENA Respiratory engages PPD, Inc. for Phase 2 COVID-19 post-exposure prophylaxis study and hVIVO for influenza challenge study to assess the efficacy of fast-acting nasal spray designed to boost innate immunity

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13 Jul 2021

ENA Respiratory Begins Phase I Study of COVID-19 Preventative Nasal Spray Designed to Stimulate Body’s Firstline Immune Defense in the Nose

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  • First-in-class, fast-acting nasal spray designed to boost innate immunity against respiratory viruses including SARS-CoV-2 and its variants, influenza and the common cold at the first entry portal for most infections
  • Company is recruiting study participants in the Sydney, Australia area
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15 Jun 2021

ENA Respiratory Advances COVID-19 Preventative Therapy through AU$32 Million Funding Round

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  • Round jointly led by Brandon Capital and Minderoo Foundation with co-investment from Uniseed will support the clinical development of INNA-051
  • Company appoints President and Chief Scientific Officer of the COPD Foundation and respiratory therapy expert Ruth Tal-Singer, Ph.D., to Board of Directors
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18 Dec 2020

ENA Respiratory announces research on preventative nasal spray, which protects against COVID-19 and common cold, published in leading peer-reviewed academic journals

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Research on preventative nasal spray, which protects against COVID-19 and common cold, published in leading peer-reviewed academic journals

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28 Sep 2020

ENA Respiratory announces an extension of its Series A and positive COVID-19 ferret challenge study results

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A novel nasal treatment developed to boost the natural human immune system to fight common colds and flu, has proved remarkably successful in reducing COVID-19 viral replication test results, released today, reveal.

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